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Upstream open reading frame : ウィキペディア英語版 | Upstream open reading frame An Upstream Open Reading Frame (uORF) is an Open Reading Frame (ORF) within the 5'UTR (5' untranslated region) of a mRNA. uORFs can regulate eukaryotic gene expression. Translation of the uORF typically inhibits downstream expression of the primary ORF. In bacteria, uORFs are called leader peptides, and were originally discovered on the basis of their impact on the regulation of genes involved in the synthesis or transport of amino acids. ==See also==
* 5'UTR * mRNA
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Upstream open reading frame」の詳細全文を読む
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